Tamoxifen is really a drug that interferes with the activity of estrogen mainly in the mammary glands of women. It has been employed to treat and stop Breast Cancer (BC) within the past 3 decades. BC cells needs estrogen to develop. Without estrogen these cells are deprived of their vital nutrition and might die. This principle is used when Tamoxifen drug was formulated. Tamoxifen binds using the estrogen receptors inside the breast thereby depriving cancer of the breast cells of significant protein in estrogen. To put it in layman's terms imagine an auditorium which has a limited number of seats and assume the auditorium manager gives advance information to everyone the well behaved people and books their tickets. The auditorium gets filled with all the good guys the unruly bad elements who come late don't get a place inside. The show inside auditorium continues without any trouble or untoward events. In this case the good guys will be the molecules inside the Tamoxifen which bind to estrogen receptors and also the bad elements are the breast cancer cells. This process can also be known as competitive antagonism. In order to buy Nolvadex online visit buynolvadexonline24.com
Tamoxifen works well only in estrogen receptor positive BC cases. It does not work on progesterone receptor breast cancers and HER2/neu (Human Epidermal growth factor Receptor 2)BC. But the nice news is the fact that almost 70% of all the cancer of the breast cases are Estrogen receptor positive ones and this drug can very effectively treat breast cancers and even prevent rid of it in advance.
But there is really a major catch and use of this drug isn't without a cost. No it doesn't pinch the wallet that much even if insurance will not cover it sometimes. Tamoxifen is over patent since 2002. It is now classified as being a generic drug. It's price has dropped drastically from the time. Even though Tamoxifen is incredibly effective it just isn't commonly prescribed as being a preventive medicine due to it's chronic unwanted effects. This drug may trigger uterine or endometrial cancer in lots of women. The risk of developing such a cancer is quadrupled even though using Tamoxifen for as low as 24 months. American Cancer Society has listed Tamoxifen like a known carcinogen. In many women this drug may cause a spurt in triglyceride levels in addition to fatty liver syndrome. Needless to say these are not good for heart or liver.
Tamoxifen may have adverse effect on the central nervous. It can severely impair cognition and memory. A good number of patients who're prescribed this drug experience an extreme drop in sexual drive and libido. As in case of any risky treatment a price benefit assessment needs to be made. Breast cancer is really a serious and fatal disease. If Tamoxifen may be assessed to be very attractive a particular patient's case then it should be used. There are well established preventive and alleviating treating the side effects caused by Tamoxifen.